During the 102nd International Association for Dental Research (IADR) General Session & Exhibition, meet our oral care product in vitro study experts. New Orleans, USA | March 13-16, 2024.
At the 2024 IADR General Session, our team of experts, will be present to provide an update on Intertek's in vitro oral care laboratory services and explain how Intertek support your product development and claim support. Intertek
has been a trusted partner of oral care product innovators and manufacturers for over 20 years.
Meet us at Booth 213 to discuss how we can support your formulation development or help you to gather scientific data to help support marketing claims or to assess the safety or performance of oral care product ingredients or formulations. Schedule an appointment now.
How our in vitro services can support your product development?
Whether you are a supplier of raw materials or an oral care product innovator, in vitro oral care product testing can be an effective approach to steer early-stage formulation development, ingredient screening and selection or formulation development and performance evaluation.
Intertek can offer a range of in vitro models to evaluate the safety and performance of oral care products or ingredients. We can also supply a range of hard tissue samples for internal R&D programmes. Finally, we can provide analytical support for oral care clinical studies.
Product Types: Our in vitro tests evaluate the following types of oral care products, toothpaste formulations, raw ingredients, mouthwash formulations, tooth gel formulations, tooth tablet or toothpowder formulations, toothbrushes, dentifrice products, interproximal cleaning devices, flosses and electronic devices such as electric toothbrushes.
Our services are targeted at the following claim areas:
Teeth Whitening: We use acellular human or bovine enamel as test substrates to evaluate the whitening efficacy of oral product formulations or ingredients. Our portfolio of tests include: pellicle cleaning ratio (PCR) x| tooth shades whiter | stain prevention | chemical stain removal | denture stain removal | mouthwash stain removal | propensity to stain | impact upon enamel gloss | ability to restore natural tooth brightness.
Dental Tubule Occlusion: We use acellular human or bovine dentine as test substrates to evaluate the ability of oral care product formulations or ingredients to block dentine tubules, which can, according to the literature, help alleviate dental sensitivity. We utilise two models: scanning electron microscope dentine occlusion studies and/or hydraulic conductance studies.
Enamel Repair & Protection: We use acellular human or bovine enamel as test substrates to evaluate the ability of oral care product formulations or ingredients to repair and protect artificial enamel lesions. Our services include pH cycling studies, surface microhardness studies and fluoride uptake studies.
Brushes and Interproximal Cleaning: We use acellular human tooth models as test substrates to evaluate the ability of oral care devices (e.g. flosses, interdental brushes or toothbrushes) to clean the interproximal regions of teeth.
Anti-plaque: We use human saliva as a test substrate to evaluate the ability of oral care product formulations or ingredients to prevent a plaque biofilm build-up, to remove dental plaque, or to buffer the pH of dental plaque to help prevent a pH drop to levels associated with demineralisation during plaque sucrose challenges.
Safety: We use acellular human or bovine enamel as test substrates to evaluate the safety of oral care product formulations or ingredients. Our services offerings include relative dentine or enamel abrasivity tests (RDA), assessing the capacity of tooth bleaching products (ISO 28399) or bespoke studies based upon individual requirements.
Clinical Study Support: We can partner with our established CRO partners to provide analytical support for clinical studies. Our analytical services can support: oral malodour studies, bioanalytical fluoride and calcium salivary clearance studies and in situ surface microhardness studies.
Hard Tissue Samples Preparation: We are licensed by the Human Tissue Authority (HTA) to store and use human teeth for research purposes. We can prepare and supply acellular enamel and dentine samples, to support your internal R&D, as well a wide range of dental restoration materials.
RESOURCES
Use this form to request our library of case studies or download using the links below:
- BROCHURE DOWNLOAD: Intertek Oral Care Product In Vitro Development Support Services
- CASE STUDY: Determining the Impact of a Toothpaste pH-Buffering System on Dental Plaque pH
- CASE STUDY: Efficacy Assessment of Interdental Brushes Through In-Vitro Studies
- CASE STUDY: Measuring Tooth Demineralisation and Remineralisation In Vitro
- CASE STUDY: Dentine Tubule Occlusion Studies
- CASE STUDY: Benchmarking Anti-Plaque Agents In Dentifrices And Mouthwashes
- CASE STUDY: Dentine and Enamel Block Preparation Supporting In-Vitro Oral Care Product Studies
The International Association for Dental Research (IADR), headquartered in Alexandria, Va. USA, is a nonprofit organization with nearly 11,000 members worldwide.
Its mission is to advance research and increase knowledge for the improvement of oral health worldwide; to support and represent the oral health research community, and to facilitate the communication and application of research findings.
