Join our webinar: Development of Drug-Nebuliser Combination Products: Formulation and Device Considerations to Ensure Success | 18 September 2024
Nebulizers offer precise delivery of high-value small molecule drugs and biologics directly to the lungs, ensuring rapid and efficient therapeutic effects. They can accommodate a wide range of formulations, including solutions, suspensions, and high viscosity drugs and encapsulated systems, making them versatile for various local and systemic treatments. Nebulizers provide consistent delivery up to very high doses, which is crucial for managing many chronic respiratory conditions. Additionally, their ease of use and the ability to integrate advanced features like breath actuation and connectivity enhance patient adherence and treatment outcomes.
During this webinar, experts from HCmed Innovations and Intertek combine their expertise to shed light on the formulation, device, and testing considerations when developing a nebulized product
Part 1: Formulation and device considerations.
• Key requirements to select a suitable delivery platform. When are mesh nebulisers a suitable delivery system?
• Advancement and new features in mesh nebulisers to improve delivery performance and usability.
• Customization platform scope, from hardware to software – fulfilling requirements of different target populations and indications.
• Data and studies that demonstrate the benefits of customizable mesh nebuliser platforms, such as Pulmogine and AdheResp.
• Formulation considerations for control of key factors such as surface tension, viscosity, osmolality and physical constraints such as device reservoir volume, and operational temperatures which can affect the fluid dynamics within the nebuliser and ultimately droplet creation.
Part 2: Understanding nebuliser performance: Analytical and performance testing
• Regulatory considerations, differences between EU and US, and how to structure studies dependent on your phase of development.
• How do we define “good nebuliser performance”, what are the key parameters to look for.
• Key analytical methods for determining performance, instrumentation needed, common analytical challenges and best practice based on hundreds of successful projects completed.
Join us for this insightful webinar - choose a session that suits your schedule:
Meet our Speakers